Dr. Sadiq and His Colleagues Believe Their Stem Cell Trials Will Treat Multiple Sclerosis

Stem Cell Clinical Trial For Multiple Sclerosis Approved by FDA

The Tisch MS Research Center of New York announced on August 14 that the FDA has given its approval to begin a clinical trial to use stem cells in the treatment of multiple sclerosis.

Main Symptoms of Multiple Sclerosis

Approximately 2.1 million people worldwide are affected by multiple sclerosis, a degenerative autoimmune disease that affects the nervous system and leads to myelin damage. According to Dr. Saud A. Sadiq, senior research scientist at Tisch, this is possibly the first effort in the U.S. that will investigate treatment of MS through direct injection of stem cells into the spinal fluid of patients. He says that the effort “represents an exciting advance in MS research and treatment.”

The MS Stem Cell Trial Team at Tisch

The Tisch MS Research Center is a unique organization with a novel approach to the treatment of multiple sclerosis. Dr. Sadiq has believed for over two decades that combining high standards of clinical care with research targeted at finding the cure to MS would improve the overall standard of treatment for MS patients. In short, at the Tisch center, your researcher is your doctor.

This is different from the standard model, where researchers spend the majority of their time conducting studies, trials, and lab work, while doctors apply the results of research in treating patients. By combining the two and allowing the doctor to conduct research tailored specifically to his patient, the center increases the pace at which discoveries can make it from lab to practice. This recent approval is evidence of the success of Dr. Sadiq’s philosophy.

The Spinal Tap of a Patient with MS

The study in question will use stem cells harvested from the subject’s own bone marrow. Patients will undergo a single bone marrow collection. From there, the appropriate stem cells will be isolated and extracted, then tested before they are injected into the patient. Once this is complete, the cells will then be injected into the fluid surrounding the patient’s spinal cord, which early tests indicate will decrease inflammation in the brain and promote repair of CNS myelin, a protein-rich substance that is necessary for healthy nervous system functioning, and a substance which multiple sclerosis causes the body to attack and destroy.

A Researcher Uses a Microscope in Stem Cell Trial for Multiple Sclerosis

In addition, early indicators are that the stem cells will also provide protection of the neurological system against the virus. Patients will receive three rounds of injections, one every three months, with safety and effectiveness being evaluated through regular follow-up appointments.

The Tisch Research Lab Is the Site of the Stem Cell Trials for Multiple Sclerosis

This application is the result of ten years of research into the use of stem cells to treat MS patients, conducted by a team of scientists headed by Dr. Sadiq and Dr. Violaine Harris, a research scientist at the Tisch Center.

Dr. Sadiq says, “This study exemplifies the Tisch MS Research Center’s dedication to translational research and provides a hope that established disability may be reversed in MS.”

For now, the trial is only a Phase I test, which means it’s still some time away from being widely and commercially available, but if successful, it could represent a major breakthrough in the treatment of MS, and could result in an increased quality of life in MS patients all over the world. Hear Dr. Sadiq talk about his hope for this clinical trial in the video.

Source:
digitaljournal.com/pr/1413282#ixzz2eabccVZo

Video Source:
youtube.com/watch?v=5ngTGlVj_hQ

Image Sources:
tischms.org
imsmp.org

14 thoughts on “Stem Cell Clinical Trial For Multiple Sclerosis Approved by FDA

  1. heavychevy662001@yahoo.com'Lisa Dale

    I have MS and I am very much interested in this “stem cell” treatment. Will it be covered by insurance?

    Reply
    1. susanhawkins@amsvans.com'Susan Hawkins

      Hi, Lisa! Thanks for your question. Since the study has just begun, and it may take some time before the results are determined, it’s unclear at this point whether insurance will cover these procedures. We’ll keep you posted.

      Reply
    1. susanhawkins@amsvans.com'Susan Hawkins

      Hi, Michelle! Dr. Saud Sadiq is heading up the trials being held at the Tisch MS Research Center of New York. They’re in the initial stage of the trial, so there’s not a great deal of information available at the moment. The web site is tischms.org, where you can find more about their work in multiple sclerosis, or you can use their “contact” page to send a direct email. We hope this helps. Thanks for following our blog!

      Reply
  2. needlesandpens@comcast.net'Terry

    So glad to read of a credible group here in the United States that is willing to look in this new direction toward restoration rather than simply the current practice of slowing progression. I am amazed that the new oral meds continue to approach MS in the same direction as the injections which have already been proven ineffective in their claimed 30% slowing. And I am as amazed that doctors who work with MS patients continue to prescribe such an approach Wishing you well with this research and the trials involved. Bless you all.

    Reply
    1. susanhawkins@amsvans.com'Susan Hawkins

      Hi, Terry! As you can see from the other comments, this is great news for people with multiple sclerosis. AMS Vans will be following the progress of these trials and keep you posted. Thanks so much for your comment and for reading our blog!

      Reply
    1. susanhawkins@amsvans.com'Susan Hawkins

      Hello, Debbie! Unfortunately, we haven’t seen any further stories on this trial. Dr. Saud Sadiq is holding the trials at the Tisch MS Research Center of New York. The web site is tischms.org– please use their “contact” page to send a direct email to learn more. We hope this helps. Thanks for reading the AMS Vans blog!

      Reply
    1. susanhawkins@amsvans.com'Susan Hawkins

      Hi, Marie! Dr. Saud Sadiq is coordinating the trials, which being held at the Tisch MS Research Center of New York. The trial is in its initial stage, and there’s not a great deal of information available at the moment. The web site is tischms.org, and you can use their “contact” page to send a direct email to learn more. We hope this helps. Thanks for reading our blog!

      Reply

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